Author: Akira Akatsuki, Nisi Oisin
There’s a killer loose in Los Angeles and super-sleuth L is on the case. Along with Naomi, a former FBI agent, he helps the LA police solve the grisly crimes. In typical Death Note fashion, things get complicated. And there’s a big surprising plot twist at the end of the book.
Rampage. Weep. Kill. Every 12 years, the 12 signs of the Chinese zodiac take the form of warriors and engage in the ultimate battle royal. They face one another in battles to the death, using all the powers of their star signs, and the sole survivor is granted the ultimate prize—a wish. Any wish. -- VIZ Media
This book concerns how estrogens are synthesized in the brain and their two modes of action on behavior: a slow process involving gene transcription and a faster action at the cell membrane. The significance of the regulation and distribution of the estrogen synthesizing enzyme aromatase in the brain is also highlighted.
The GnRH Neuron and its Control examines the developmental biology of GnRH neurons including their birth in the nasal placode of the early embryo, perinatal programming, and sexual differentiation, in addition to the hypothalamic mechanisms that control GnRH neurons in adulthood to generate pulsatile and surge modes of GnRH secretion throughout the major life stages including aging. The morphology, electrophysiology, signal transduction pathways, transcriptional regulators, and genomics underlying function of the adult GnRH neuron is discussed in detail, as is the neuroendocrinology and cell biology governing the generation of both modes of GnRH release. The book also reviews the neurobiological mechanisms and circuitry responsible for the modulation of the activity of GnRH neurons by season, stress, nutrition, and metabolism, and covers the current and potential therapeutic approaches to regulating GnRH secretion and action. Filled with newly identified research and classical fundamental knowledge to GnRH biology, it will provide students, researchers, and practitioners with an in-depth understanding of reproductive neuroendocrinology. This is the fifth volume in the Masterclass in Neuroendocrinology Series, a co- publication between Wiley and the INF (International Neuroendocrine Federation) that aims to illustrate highest standards and encourage the use of the latest technologies in basic and clinical research and hopes to provide inspiration for further exploration into the exciting field of neuroendocrinology.
Author: Masato Kinoshita, Kenji Murata, Kiyoshi Naruse, Minoru Tanaka
Publisher: John Wiley & Sons
The zebrafish is the most important fish model in developmental and genetic analyses. This book contains 19 review articles covering a broad spectrum of topics, from development to genetic tools. The contents range from early development, the role of maternal factors and gastrulation, to tissue differentiation and organogenesis, such as development of the organizer, notochord, floor plate, nervous system, somites, muscle, skeleton and endoderm. The genetic tools cover morpholino knock-down, transgenics, fish cloning, transposons and genome evolution. The book also includes two chapters on genome mapping and embryonic stem cells in medaka, another important model fish. Summarizing the state-of-the-art studies of the zebrafish model and focusing on the molecular aspects of development, this book is a valuable reference for students learning the basic aspects of the zebrafish model, and for researchers seeking resources in zebrafish research. Contents:The Role of Maternal Factors in Early Zebrafish Development (F Pelegri)Gastrulation in Zebrafish (F Ulrich & C-P Heisenberg)Development of the Zebrafish Organiser and Notochord (K A Thomas & D L Stemple)Formation and Functions of the Floor Plate (J Tian & K Sampath)Form and Function in the Zebrafish Nervous System (M Hendricks & S Jesuthasan)Development of the Primary Nervous System of the Zebrafish Embryo (U Strähle & V Korzh)Making Scents: Development and Function of the Olfactory Sensory System (K E Whitlock)Somites Segmentation: A View from Fish (H Takeda & Y Saga)Vertebrate Somite Development, Notch Signaling and Others (Y-J Jiang)Molecular Regulation of Fish Muscle Development and Growth (S J Du)Skeletogenesis in Zebrafish Danio rerio: Evolutionary and Developmental Aspects (S Fisher & P M Mabee)Endoderm Formation in Zebrafish (N B David et al.)Gene 'Knockdown' Approaches Using Unconventional Antisense Oligonucleotides (E Chen et al.)Transgenic Fish for Developmental Biology Studies (Z-Y Gong et al.)Cloning the Zebrafish (B Ju et al.)Applications of Transponsable Elements in Fish for Transgenesis and Functional Genomics (P B Hacketts et al.)Evolution of the Zebrafish Genome (J H Postlethwait)Medaka Genome Mappling for Functional Genomics (H Mitani et al.)Medaka Embryonic Stem Cells (Y-H Hong & M Schartl) Readership: Upper level undergraduates, graduate students, academics and researchers in cell & molecular biology, fish & marine biology and genetics. Keywords:Zebrafish;Medaka;Embrynonic Development;Axial Structures;Neurogenesis;Somites;Transgenics;GenomeKey Features:Contributed by active researchers working in the field of developmental biology of the zebrafish and medakaCovers essentially all major topics from early development to organogenesis as well as several most important genetic toolsRepresents most updated reviews in selected areas of the rapidly developing field
This series of volumes represents a comprehensive and integrated treatment of reproduction in vertebrates from fishes of all sorts through mammals. It is designed to provide a readable, coordinated description of reproductive basics in each group of vertebrates as well as an introduction to the latest trends in reproductive research and our understanding of reproductive events. Whereas each chapter and each volume is intended to stand alone as a review of that topic or vertebrate group, respectively, the volumes are prepared so as to provide a thorough topical treatment across the vertebrates. Terminology has been standardized across the volumes to reduce confusion where multiple names exist in the literature, and a comprehensive glossary of these terms and their alternative names is provided. * A complete, essential and up to date reference for research scientists working on vertebrate hormones and reproduction - and on animlals as models in human reproductive research. * Covers the endocrinology, neuroendocrinology, physiology, behaviour and anatomy of vertebrate reproduction. * Structured coverage of the major themes for all five vertebrate groups allows a consistent treatment for all. * Special chapters elaborate on features specific to individual vertebrate groups and to comparative aspects, similarities and differences between them.
Author: Kiyoshi Naruse, Minoru Tanaka, Hiroyuki Takeda
Publisher: Springer Science & Business Media
Oryzias latipes, known as medaka, is a model organism from East Asia. Breeding of this small, egg-laying freshwater teleost fish has long been popular among hobbyists in Japan. Now, as biological science has entered the genome era, the medaka provides significant advantages that make it one of the most valuable vertebrate models: a large collection of spontaneous mutants collected over a century, the presence of highly polymorphic inbred lines established over decades, and a recently completed genome sequence. This book is the first comprehensive monograph to cover a variety of medaka research. It opens with a historical view of medaka, followed by a series of research topics in the four major areas where the medaka is increasingly important: genomics, genetics, and resources; organogenesis and disease models; germ cells, sex determination, and reproduction; and evolution. Readers will find state-of-the-art information on medaka genetics and genomics such as the first isolation of active transposons in vertebrates, the influence of chromatin structure on sequence variation, fine QTL analysis, and versatile mutants as human disease models.
Author: Akira Toriyama
Publisher: VIZ Media LLC
In the far future, war has destroyed the entire Earth, leaving only a barren wasteland where the supply of water is controlled by the greedy king. In search of a long-lost lake, Sheriff Rao asked the king of the demons for help...and got the king's son, Beelzebub, and his assistant, Thief. Together the unlikely trio sets off across the desert, facing dragons, bandits and the deadliest foe of all... the King's army itself! It's travel adventure and tank action in this new story from Akira Toriyama, the creator of Dragon Ball Z! -- VIZ Media
Author: Ryu Fujisaki
Publisher: VIZ Media LLC
In the ultimate war of man vs. machine, the fate of humanity lies with a teenage cyborg named Shio! R to L (Japanese Style). In the ultimate war of man vs. machine, the fate of humanity lies with a teenage cyborg named Shio! Vow of the Rose: Shio and friends are on their way to Spider's Thread to rescue Kami, but before they can do that Shio must battle his resurrected father and learn the true history of Waq Waq!
This series of volumes represents a comprehensive and integrated treatment of reproduction in vertebrates from fishes of all sorts through mammals. It is designed to provide a readable, coordinated description of reproductive basics in each group of vertebrates as well as an introduction to the latest trends in reproductive research and our understanding of reproductive events. Whereas each chapter and each volume is intended to stand alone as a review of that topic or vertebrate group, respectively, the volumes are prepared so as to provide a thorough topical treatment across the vertebrates. Terminology has been standardized across the volumes to reduce confusion where multiple names exist in the literature, and a comprehensive glossary of these terms and their alternative names is provided. A complete, essential and up to date reference for research scientists working on vertebrate hormones and reproduction - and on animlals as models in human reproductive research Covers the endocrinology, neuroendocrinology, physiology, behaviour and anatomy of vertebrate reproduction Structured coverage of the major themes for all five vertebrate groups allows a consistent treatment for all Special chapters elaborate on features specific to individual vertebrate groups and to comparative aspects, similarities and differences between them
A complete guide to endonuclease-based genomic engineering, from basic science to application in disease biology and clinical treatment.
The Dangerous Days of Daniel X
Author: James Patterson, Michael Ledwidge
Publisher: Little Brown & Company
Possessing supernatural abilities that enable him to change animals, objects, and himself into any shape of his choosing, Daniel protects the earth from alien predators while seeking the entities responsible for the murders of his parents.